Toward a Life Without Daily Insulin Injections

Worldwide, over 500,000 people are affected by unstable Type 1 Diabetes. BIOPI's innovative bioartificial pancreas encapsulates insulin-secreting cells in patented 3D hydrogels, enabling autonomous glucose regulation without immunosuppressants, using non-human cells for scalability and long-term durability.

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Our Revolutionary Innovation

The BIOPI Difference

BIOPI is pioneering a bioartificial pancreas: an implantable device that encapsulates insulin-secreting cells in unique, patented 3D hydrogels. This fosters cell survival, immunoisolation, and compatibility with non-human cells, overcoming limitations of traditional therapies.

Advanced Immunoprotection

Hydrogels shield cells from immune rejection while permitting essential diffusion.

Optimized Microenvironment

3D matrix ensures oxygen, nutrients, and long-term viability.

Dynamic Glucose Sensing

Real-time insulin secretion mimics natural pancreatic function.

Sustainable Design

Engineered for longevity and easy maintenance.

Transformative Impact

  • Seamless, autonomous insulin management
  • Eliminate lifelong immunosuppressant therapy
  • Enhance longevity and daily quality of life
  • Minimize hypoglycemia and stabilize glycemia

Disclaimer: Investigational device in pre-clinical phase. Functional prototype developed; not yet available for sale.

How Our Bioartificial Pancreas Works

1. Cell Sourcing

High-quality insulin-secreting islets from GMP-compliant sources, including non-human origins.

2. Innovative Encapsulation

Patented 3D hydrogels create a protective, biocompatible niche for cells.

3. Nutrient Optimization

Advanced matrix design sustains oxygen and nutrient delivery for cell health.

4. Responsive Regulation

Cells dynamically respond to glucose levels, secreting insulin autonomously.

Milestones, Team & Labs

Key Milestones

  • 2024 Deep Impact Award - Jury Special Prize
  • 2025 Top 5 Medtech/Biotech at Tech&Fest
  • Ongoing Pre-clinical testing of functional prototype
  • Ongoing Strategic partnerships with top institutions
Watch Award Presentation

Our Expert Team

A collaborative team of 7 researchers, physicians, and engineers specializing in biomaterials, cell theraby, and implantable medical devices.

Portrait of Ibrahim Shalayel, Project Leader at BIOPI
Ibrahim Shalayel
Project Leader & Entrepreneur

Collaborating Laboratories

Key Partners

Empowered by Leading Partners

Frequently Asked Questions

BIOPI's approach eliminates the need for human donors and immunosuppressants by using patented 3D hydrogels for cell encapsulation, enabling scalable use of non-human cells while ensuring long-term function.

Our functional prototype is in pre-clinical testing. We're advancing toward clinical trials with strong institutional support.

It offers freedom from daily injections, reduces health risks, and improves overall well-being through autonomous, maintenance-free glucose control.

Clinical trials are upcoming. Reach out via contact form to stay informed about participation opportunities.

Connect With Us

We're open to collaborations, investments, media, and partnerships. Based at TIMC Lab, Grenoble, France.

contact@bio-pi.com
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